Alcuni contaminanti ambientali sono non biodegradabili e pericolosi per la salute umana con effetti tossici su svariati target nell’organismo. Ad oggi diversi studi suggeriscono il legame di alcuni di questi contaminanti ...

Cancer is one of the leading causes of death throughout the world and the number of cases per year is reported to rise to 23.6 million by 2030. Amongst the different types of treatments available, chemotherapy represent ...

Short circulating half-life and poor plasma stability and solubility remain key challenges in the field of therapeutic peptide; to overcome these limitations we decided to take advantage of serum albumin, a protein that ...

Aquaculture currently supplies more than half of all human consumption of fish and seafood, and is expected to grow even further to meet future demand. However, these intensive farming models, together with climate change, ...

Cancer is a vast group of diseases caused by mutations in the human DNA that result in an uncontrollable growth of cells which can spread around the body. Cancer is one of the leading causes of mortality worldwide. Advancements ...

L' Osteoartrite (OA) è una malattia degenerativa delle articolazioni che porta a dolore cronico e disabilità. È la forma più comune di artrite, colpisce circa il 3% della popolazione, determinando così un grave onere ...

I peptidi sono sempre più impiegati come agenti terapeutici per diverse malattie. Possiedono caratteristiche intermedie tra i farmaci chimici e biologici come dimensioni inferiori, sintetizzabili chimicamente, facilmente ...

The human serum albumin is the drug carrier for many substances within the human body. The aim of this thesis is to identify the binding epitope of a lipid-modified peptide able to bind serum albumin with high affinity and ...