Exploring environmental quality and human health relationships : a risk-based tool for ranking environmental chemical stressors at the regional scale

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dc.contributor.advisor Marcomini, Antonio it_IT
dc.contributor.author Giubilato, Elisa <1980> it_IT
dc.date.accessioned 2012-05-24T10:56:10Z it_IT
dc.date.accessioned 2012-07-30T16:05:34Z
dc.date.available 2013-11-04T10:32:18Z
dc.date.issued 2012-03-29 it_IT
dc.identifier.uri http://hdl.handle.net/10579/1205 it_IT
dc.description.abstract The EU Environment and Health Strategy (2003) asks for the development of innovative tools for health risk and impact assessment, including screening methods suitable to identify the most critical scenarios. A “Risk-based Tool for the Regional Ranking of Environmental Chemical Stressors” has been developed to support decision-makers in the identification of priority environmental contaminants, as well as priority areas, to be further assessed. The tool implements, through a Multi-Criteria Decision Analysis procedure, a quantitative Weight-of-Evidence approach integrating data on environmental contamination, exposure biomarkers and health effects. The tool has been applied to a case-study in Flanders (Belgium), using soil contamination data and data on biomarkers of exposure and effect measured in adolescents. A Monte Carlo-based sensitivity analysis permits to investigate the role of criteria weights in influencing the final ranking of chemical stressors. it_IT
dc.description.abstract La Strategia Europea per l’Ambiente e la Salute chiede lo sviluppo di strumenti innovativi per la valutazione di rischi e impatti sanitari, inclusi metodi di screening per identificare gli scenari più pericolosi. Uno strumento per la prioritizzazione a scala regionale degli stressori ambientali chimici sulla base del rischio posto per la salute umana è stato sviluppato per supportare i decisori nell’individuare i contaminanti e le aree prioritarie da analizzare in dettaglio. Lo strumento implementa, attraverso l’Analisi Multi-Criteriale, un approccio Weight-of-Evidence che integra dati di contaminazione ambientale, biomarker di esposizione ed effetti sanitari. La metodologia è stata applicata ad un caso studio nella regione delle Fiandre, utilizzando dati di contaminazione del suolo e biomarker di esposizione ed effetto misurati in adolescenti. L’analisi di sensitività ha permesso di analizzare il ruolo dei pesi attribuiti ai criteri nell’influenzare il ranking finale delle sostanze. it_IT
dc.format.medium Tesi cartacea it_IT
dc.language.iso en it_IT
dc.publisher Università Ca' Foscari Venezia it_IT
dc.rights © Elisa Giubilato, 2012 it_IT
dc.subject Ambiente it_IT
dc.subject Salute it_IT
dc.subject Rischio it_IT
dc.subject Prioritizzazione it_IT
dc.subject Stressore it_IT
dc.title Exploring environmental quality and human health relationships : a risk-based tool for ranking environmental chemical stressors at the regional scale it_IT
dc.type Doctoral Thesis it_IT
dc.degree.name Scienze ambientali it_IT
dc.degree.level Dottorato di ricerca it_IT
dc.degree.grantor Scuola di dottorato in Scienze e tecnologie (SDST) it_IT
dc.description.academicyear 2009/2010 it_IT
dc.description.cycle 23 it_IT
dc.degree.coordinator Pavoni, Bruno it_IT
dc.location.shelfmark D001135 it_IT
dc.location Venezia, Archivio Università Ca' Foscari, Tesi Dottorato it_IT
dc.rights.accessrights openAccess it_IT
dc.thesis.matricno 955528 it_IT
dc.format.pagenumber 165 p. it_IT
dc.subject.miur CHIM/12 CHIMICA DELL'AMBIENTE E DEI BENI CULTURALI it_IT
dc.description.tableofcontent Table of contents 1 Summary 4 Sommario 6 List of contributions 8 1-Introduction 10 2-Environment and Health Policies and Research Initiatives in Europe 18 3-Environmental Health Assessment Frameworks and Tools 27 4-Dealing with uncertainty in health risk assessment 55 5-Development of a tool for ranking environmental chemical stressors at the regional scale 82 6-Case-study: soil contamination and adolescents’ health in Flanders (Belgium) 106 7-Sensitivity analysis 139 8-Conclusions 155 Acknowledgements 158 ANNEX1-Monitoring data used in the Flemish case-study 159 it_IT
dc.identifier.bibliographiccitation Giubilato, Elisa. "Exploring environmental quality and human health relationships : a risk-based tool for ranking environmental chemical stressors at the regional scale", Università Ca' Foscari Venezia, Tesi di Dottorato, 23. ciclo, 2012 it_IT
dc.degree.discipline Scienze ambientali it_IT


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